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FLU-pretreated donor T cells engraft and expand, but do not activate in allogeneic recipients Glucocorticoids are known to cause apoptosis in lymphocytes, and we found that after 16 h in culture, there was a significant reduction of T and B lymphocyte viability in the FLU-treated group compared to the vehicle control, with little effect on macrophages or granulocytes (Figs 3A and EV3A).
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