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Benign and malignant tumours of the ampulla of Vater (hereafter referred to as ampullary tumours) are relatively rare. For example, in the Netherlands, there were 177 patients with ampullary tumours in 2021 (0.68 per 100 000 in 2010–2016)1,2. Benign tumours have a 26– 65% lifetime risk of becoming malignant3,4.
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