To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. FiguresCardiac allograft vasculopathy (CAV) limits long-term patient survival and graft outcomes after heart transplantation. Early epicardial intimal disease and diffuse epicardial and microvascular coronary involvement in CAV are problematic for noninvasive diagnosis. We have shown impaired myocardial blood flow (MBF) quantification in patients with CAV.