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BACKGROUND TRPM7 is a cation channel permeable to Mg2+ and Ca2+ bound to an alpha-kinase domain with important role in cell homeostasis. We demonstrated that TRPM7 is protective against cardiac inflammation and dysfunction. Here, we investigated the importance of TRPM7-Mg2+ in inflammatory response and oxidative stress in cardiac fibroblasts in the context of hypertension induced by aldosterone and salt.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
