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Highlights • Tricuspid regurgitation is associated with significant morbidity and mortality, and currently off-label transcatheter leaflet repair using the MitraClip system is the most commonly used intervention for patients with severe TR and heart failure.
Mitral regurgitation (MR) is the most common valvular heart disease in the world. The natural history of MR in the modern era has been well documented and is not benign.
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