Introduction Hepatocellular carcinoma (HCC) is a widespread solid malignancy and the third leading cause of cancer-related deaths worldwide.1,2 Its estimated annual incidence is projected to exceed 1,000,000 cases by 2025.3 Resection is the most common cure for HCC worldwide, notably, according to the Chinese official guidelines and the clinical experience of our center and other country centers, intermediate and advanced-stage HCC patients could undergo resection, which is associated with...