Research Article | Molecular Biology and Physiology Sébastien Lacroix, Florent Pechereau, Nadine Leblanc, Besma Boubertakh, Alain Houde, Cyril Martin, Nicolas Flamand, Cristoforo Silvestri, Frédéric Raymond, Vincenzo Di Marzo, Alain Veilleux Lawrence A. David, Editor DOI: 10.1128/mSystems.00407-19 ABSTRACT The intestinal microbiota and the expanded endocannabinoid (eCB) system, or endocannabinoidome (eCBome), have both been implicated in diet-induced obesity and dysmetabolism.