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Articles by Francisco Aquino
Stroke risk in cancer survivors: A meta-analysis and meta regression - Neurological Sciences
Abstract It is suggested that survivors of different types of cancer may have an increased risk of stroke. Our study aims to evaluate cancer patients and non-cancer controls by analyzing stroke events in each group. Previous studies concluded that certain types of cancer increased stroke risk, however, their results had significant heterogeneity and statistical concerns.
Association between antidepressant use and gynecological cancer risk: a systematic review and meta-analysis - European Journal of Clinical Pharmacology
Abstract The potential carcinogenic effects of antidepressants (ADs) have been debated, with some preclinical studies suggesting associations with tumor promotion. However, clinical evidence regarding their impact on the risk of gynecological cancers remains limited and inconclusive, necessitating further investigation. Therefore we conducted a comprehensive search in PubMed, Embase, and Web of Science for studies examining the correlation between AD use and the risk of gynecological cancers.
A los dos años de tu partida…Papi Álvarez Castellanos
Cómo pasa el tiempo! Hoy arribamos al segundo aniversario del día que Dios te reclamó, cumpliendo con su perfecto Plan para tu vida, la de aquí y la de allá, donde el último latido de tu corazón en la tierra fue celebrado por Cristo, nuestro salvador, de quién casi pude escuchar en ese momento decir… consumado es…y así fue…ya estabas listo para de Su mano partir hacia Su hogar donde, desde hace siglos ya había preparado moradas para ti y los suyos.
A propósito del proyecto de ley que modifica la Ley No. 631-16 para el Control y Regulación de Armas
La degradación de valores que en el mundo contemporáneo se experimenta, constituye una preocupación ascendente entre los líderes de las naciones, sean políticos, religiosos, educativos, sociales o seanmeros individuos que transitan en medio de estos difíciles tiempos.
Pathologic response rates in HER2-low versus HER2-zero early breast cancer patients receiving neoadjuvant therapy: a systematic review and meta-analysis | Breast Cancer Research
Abstract Currently, the primary methods for detecting HER2 expression levels are immunohistochemistry (IHC) and in situ hybridization (ISH), with the traditional standard being a HER2-positive score of 3 + accompanied by ERBB2 gene amplification detected through ISH. However, a new entity has recently emerged: HER2-low, defined as HER2 IHC 1 + or 2 + with negative ISH.
Efficacy and safety of PD-1/PD-L1 inhibitors in patients with Merkel Cell Carcinoma: a systematic review and Meta-analysis - BMC Cancer
References D’Angelo SP, Bhatia S, Brohl AS, Hamid O, Mehnert JM, Terheyden P, et al. Avelumab in patients with previously treated metastatic Merkel cell carcinoma: long-term data and biomarker analyses from the single-arm phase 2 JAVELIN Merkel 200 trial. J Immunother Cancer. 2020;8:e000674. Article PubMed PubMed Central Google Scholar Schadendorf D, Lebbé C, Zur Hausen A, Avril M-F, Hariharan S, Bharmal M, et al. Merkel cell carcinoma: pidemiology, prognosis, therapy and unmet medical needs.
Gastric cancer burden and regional disparities among Helicobacter pylori–positive patients in the Americas: a systematic review and meta-analysis - Clinical and Translational Oncology
Abstract Helicobacter pylori infection is a significant risk factor for gastric cancer (GC), particularly in populations across the Americas. Previous studies have suggested a link between HP and GC, but variability in prevalence across regions has yet to be fully explored. The aim of this study is to quantify the prevalence of GC in HP-positive patients across the Americas, identifying disparities by country, region, and demographic factors.
Pharmacogenetics of DPYD and treatment-related mortality on fluoropyrimidine chemotherapy for cancer patients: a meta-analysis and trial sequential analysis | BMC Cancer | Full Text
As described in PRISMA flow diagram (Fig. 1), a total of 9,685 studies were assessed in our systematic search. After the removal of duplicates and the screening of titles or abstracts, 93 manuscripts were eligible to be thoroughly reviewed for inclusion and exclusion criteria. Finally, 36 studies, encompassing a population of 16,005 patients, formed the scope of the analysis [32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67].
The incidence risk of gynecological cancer by antipsychotic use: a meta-analysis of 50,402 patients - BMC Cancer
Abstract Female gynecological cancers represent a serious public health problem, with 1,398,601 new diagnoses and 671,875 deaths per year worldwide. Antipsychotics are often used in psychiatric disorders, including schizophrenia, bipolar disorder, and major depression. It is estimated that the prescription of these drugs is linked to 1,800 deaths a year in the United States, but their association with cancer remains controversial.
The incidence risk of gynecological cancer by antipsychotic use: a meta-analysis of 50,402 patients - BMC Cancer
This systematic review followed the Cochrane’s Collaboration and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines [20]. The protocol was prospectively registered in the International Prospective Register of Systematic Reviews (PROSPERO) with registration number CRD42023486704.
Efficacy and safety of Zolbetuximab plus chemotherapy for advanced CLDN18.2-positive gastric or gastro-oesophageal adenocarcinoma: a meta-analysis of randomized clinical trials | BMC Cancer | Full Text
This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines [27]. The protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO) with registration number CRD42023455827.
PD-1/PD-L1 inhibitors plus carboplatin and paclitaxel compared with carboplatin and paclitaxel in primary advanced or recurrent endometrial cancer: a systematic review and meta-analysis of randomized clinical trials | BMC Cancer | Full Text
This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines [20]. The protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO) with registration number CRD42023445890.
Nuestro apoyo sincero a Miriam Germán
Antes de ayer hice acto de presencia en la reunión propiciada por un grupo de activistas sociales, cuyos designios era pronunciarse en apoyo de Miriam Germán a propósito de las amenazas que ella y su hijo han recibido, cuya autoría en realidad desconocemos pero basta la simple existencia del mensaje para generar la alarma nacional que ciertamente ha despertado.
Debates en los juicios de corrupción
Advertencia: Lo escrito en los párrafos siguientes, aunque lo menciona como punto de partida para reflexionar, no contiene juicio de valores respecto del caso del sometimiento de un respetado abogado de la defensa en uno de los casos de corrupción que cursan en nuestro tribunales.
'Trabalho num dos locais mais isolados, inóspitos e ventosos do planeta', conta cientista brasileiro
Pesquisador-chefe de uma base 2.500 quilômetros ao sul da Estação Antártica Comandante Ferraz e a apenas 600 quilômetros do Polo Sul, “Chico Geleira” não vê a hora de voltar ao isolamento do continente gelado Francisco Eliseu Aquino, em depoimento a Renato Grandelle 14/08/2020 - 03:00 O geógrafo Francisco Eliseu Aquino diante do Criosfera 1, o módulo onde faz pesquisas há oito anos.
Fast and direct detection of metal accumulation in marine sediments using laser-induced breakdown spectroscopy (LIBS): a case study from the Bay of Cienfuegos, Cuba - Analytical Methods (RSC Publishing)
Laser-induced breakdown spectroscopy (LIBS) is an emerging, multi-elemental and green technique, particularly suitable for the direct analysis of solid samples. In this study, thirty-two superficial sediments collected in Cienfuegos Bay in 2011-2013 were analyzed by LIBS without requiring sample digestion. Aluminium, Ca, Fe, K, Mg, Mn, Na and Ti emission lines were detected in all samples.
Method proposition for production of acrylonitrile-butadiene-styrene (ABS) and polycarbonate (PC)/ABS standards for directly Sb determination in plastics from e-waste using laser-induced breakdown spectroscopy (LIBS) - Journal of Analytical Atomic Spectro
This study shows a procedure for directly Sb determination in e-waste solid samples (polymers). Polymer standards (acrylonitrile-butadiene-styrene (ABS) and polycarbonate (PC)/ABS) were mixed with dichloromethane solution for homogenization, dried, milled and sieved. The obtained powder was mixed with Sb2O3 and pressed in a thermopress. A calibration curve (Sb: 0 to 2.6% w/w) was prepared and analysed using LIBS (Laser-induced breakdown spectroscopy) and more than 10000 spectra obtained.
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