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1. Introduction Cooperative intelligent transport systems (C-ITSs) are vehicles that exchange information directly with other C-ITSs [1]. Depending on the communication partner, a distinction is made between vehicle-to-vehicle (V2V), vehicle-to-infrastructure (V2I), and vehicle-to-person (V2P) communication, which can be summarized by the general term vehicle-to-X (V2X) communication [2].
1. Introduction Installing advanced driver assistance systems (ADASs) in vehicles is intended to increase road safety and driving comfort [1,2]. There are vehicles on the market today with partially automated driving functions (SAE Level 2) on board [3]. These systems can take over both longitudinal and lateral control of the vehicle for a limited period of time. Taking over the driving task is associated with automation risks resulting from limitations or malfunctions the driver must control [4].
Summary Neurological conditions represent an important driver of paediatric disability burden worldwide. Measurement of serum neurofilament light chain (sNfL) concentrations, a specific marker of neuroaxonal injury, has the potential to contribute to the management of children with such conditions. In this context, the European Medicines Agency recently declared age-adjusted reference values for sNfL a top research priority.
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