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1 INTRODUCTION Synthetic cannabinoids (SC) were initially developed as research substances several decades ago.1 With few exceptions, the discovered substances were not suitable for therapeutic use due to pronounced central nervous effects. Approximately 15 years ago, the substance class gained popularity as a legal alternative to conventional drugs of abuse.
Abstract New Synthetic Opioids (NSOs) are one class of New Psychoactive Substances (NPS) enjoying increasing popularity in Europe. Data on their toxicological or metabolic properties have not yet been published for most of them.
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