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Antibody-drug conjugates (ADCs) are an emerging type of biotherapeutics. Consisting of an antibody conjugated to small drug molecules through a variety of linkers, this type of therapeutics is challenging to analyse. Several different linker designs, to limit the release of the cytotoxic drug to as close in proximity to the tumour as possible, and multiple variations of tissue specific antibodies sum up to a chemically very complex set of analytes.
R. Neupane, M. Källsten, F. Lehmann and J. Bergquist, Anal. Methods, 2017, Accepted Manuscript , DOI: 10.1039/C7AY02696J If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using RightsLink. Go to our Instructions for using RightsLink page for details.
R. Neupane, M. Källsten, F. Lehmann and J. Bergquist, Anal. Methods, 2018, Advance Article , DOI: 10.1039/C7AY02696J If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using RightsLink. Go to our Instructions for using RightsLink page for details.
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