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Abstract Introduction: Lyme arthritis (LA) involves complex immune dysregulation, and macrophages contribute centrally to persistent joint inflammation. However, synovial macrophage heterogeneity and its potential relevance to therapeutic intervention remain incompletely defined. Methods: We integrated scRNA-seq data from Borrelia burgdorferi (Bb)-infected murine joints (GSE233850) with bulk RNA-seq data (GSE283617).
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.