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We previously reported in atrial myocytes that inhibition of cAMP-dependent protein kinase (PKA) by laminin (LMN)-integrin signaling activates ? -adrenergic receptor (? -AR) stimulation of cytosolic phospholipase A (cPLA ). The present study sought to determine the signaling mechanisms by which inhibition of PKA activates ? -AR stimulation of cPLA . We therefore determined the effects of zinterol (0.1 ?M; zint-?
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