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Gabrianne Larson on Muck Rack

Gabrianne Larson

As seen in: Nature, UroToday
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Articles by Gabrianne Larson

Targeted proteomics for the detection of androgen receptor variants in preclinical models of castration-resistant prostate cancer.

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By Zoi E. Sychev, Gabrianne Larson, Megan L. Ludwig
| UroToday Verified
The emergence of Androgen Receptor variants (AR-Vs) during hormonal treatment is believed to be one of the key mechanisms of resistance.
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Integrated multi-omics assessment of lineage plasticity in a prostate cancer patient with brain and dural metastases - npj Precision Oncology

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By Megan L. Ludwig, Hannah E Bergom, Justin H. Hwang, David Moline, Gabrianne Larson
| Nature Verified
Abstract Metastases to the brain are rare in prostate cancer. Here, we describe a patient with two treatment-emergent metastatic lesions, one to the brain with neuroendocrine prostate cancer (NEPC) histology and one to the dural membrane of adenocarcinoma histology. We performed genomic, transcriptomic, and proteomic characterization of these lesions and the primary tumor to investigate molecular features promoting these metastases.
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