Introduction The outcomes of patients treated with a Fontan procedure, a palliative surgical procedure used for univentricular heart defects, have improved remarkably in recent decades.1 Due to improvements in diagnosis and surgical strategy, patients with a Fontan circulation can now have a higher quality of life and increased life expectancy than before.2 Nevertheless, these patients continue to have impaired exercise capacity, which is an important prognostic predictor of morbidity and...