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Abstract Progression in early Parkinson's disease (PD) is heterogeneous, motivating transparent biological markers of group-level progression context. We analyzed longitudinal Parkinson’s Progression Markers Initiative (PPMI) data downloaded on 31 May 2026. The neuroimmune-enriched multibiofluid proteomic index (NEMPI) used 718 quality-control-eligible cerebrospinal fluid and plasma markers, organized into four source-context modules with equal marker and module weights.
1College of Information Engineering, Henan University of Science and Technology, Luoyang, China 2The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China Introduction: Epilepsy is a neurological disorder characterized by abnormal neuronal discharges in the brain, posing a persistent challenge in clinical diagnosis.
The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China College of Information Engineering, Henan University of Science and Technology, Luoyang, China Introduction: Brain tumors present a significant threat to human health, demanding accurate diagnostic and therapeutic strategies.
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