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Visible light-induced direct alkylation of the purine C8-H bond with ethers Changtong Lu, Gary Histand and Dongen Lin Abstract The one-step visible light-induced direct alkylation of the C8-H bond for purine derivatives by ethers was developed using Eosin Y as the photocatalyst and t-BuOOH as the oxidant at room temperature. This method describes the coupling of the α-C of the ether to the C8 of purine.
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