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Ninety-three participants with prodromal AD, according to the International Working Group-1 criteria [34], were recruited from memory clinics in Stockholm, Sweden, and Toulouse, France, through media advertisements in Frankfurt, Germany, and from previous research cohorts in Kuopio, Finland, via the university hospital neurology clinic.
A low-protein diet (LPD) is recommended to patients with advanced chronic kidney disease (CKD) to delay kidney decline progression and improve quality of life [1]. A LPD needs to be prescribed under careful considerations to avoid protein energy wasting (PEW), since a decrease in appetite, development of a poor nutritional status and weight loss begin relatively early in the course of CKD [2–5].
A low protein diet (LPD) is recommended to patients with advanced chronic kidney disease (CKD), whereas geriatric guidelines recommend a higher amount of protein. The aim of this study was to evaluate the safety of LPD treatment in older adults with advanced CKD. The EQUAL study is a prospective, observational study, including patients ≥65 years, incident estimated glomerular filtration rate <20 ml/min/1.73m², in six European countries with follow-up up till six years.
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