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Abstract Cisplatin is a widely deployed chemotherapeutic agent whose clinical utility is constrained by dose-limiting toxicities, including injury to the submandibular salivary gland mediated primarily by oxidative stress-driven apoptosis and progressive fibrotic remodeling. This study investigated the protective potential of Nanopropolis against cisplatin-induced structural, molecular, and ultrastructural alterations in the rat submandibular gland.
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