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Purpose To investigate efficacy 1 year after implantation of a novel glaucoma tube shunt, the PAUL Glaucoma Implant (PGI; Advanced Ophthalmic Innovations, Singapore, Republic of Singapore), in the treatment of eyes with refractory glaucoma. Design Clinical trial. Participants Glaucoma patients who are recalcitrant to maximum tolerated medical therapy and require tube shunt surgery.
In the present study, we evaluated macular and peripapillary choroidal thickness in LHON patients. Overall, we found that both macular and peripapillary choroidal thicknesses increased in the acute stage. Moreover, we showed a decreased macular choroidal thickness in the chronic stage. Most importantly, we have evidence that the increased thickness of axons preceded the changes of choroidal thickness, suggesting that one event may lead to the other.
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