To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Introduction: Tumour stroma resembles a non-healing wound, where a procoagulant environment creates a permissive milieu for cancer growth. However we have previously shown that stromal fibroblasts develop a procoagulant phenotype at the preinvasive stage. We aimed to determine whether procoagulant fibroblasts are functional in tumour development.