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Ginger Rakestraw

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Articles by Ginger Rakestraw

Hypertensive stress rewires macrophage signaling in heart failure with preserved ejection fraction independent of obesity

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By Yuya Kinoshita, Michio Sato, Tsuyoshi Kadomatsu, Manami Katoh, Kazutaka Ikeda, Goro Yoshioka, Yuya Matsue, Wataru Fujimoto, Atsushi Kurabayashi, Daisuke Torigoe, Tomohiko Wakayama, Haruki Horiguchi, Aaron P. Yamniuk, Leonard Adam, Keishi Miyata, Takanori Yamaguchi, Hiromasa Otake, Tohru Minamino, Seitaro Nomura, Kimitoshi Nakamura, Koichi Node, Yuichi Oike, Yusuke Okadome, Ryoko Kusaba, Xu Peiwen, Burçe Ergel Gurbuzbalaban, Ginger Rakestraw
| Nature Verified
Abstract Heart failure with preserved ejection fraction (HFpEF) remains a major unmet clinical challenge. Although obesity is common in many HFpEF cohorts from Europe and North America, three Japanese HFpEF cohorts identified hypertension and sympathetic overactivation, rather than obesity, as dominant features.
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