The brain‐derived neurotrophic factor (BDNF) is a major participant in the regulation of food intake and may play a role in the regulation of the stress response. We aimed to investigate whether there is a gene‐environment interaction in the relationship between stress and BDNF Val66Met polymorphism in relation to dietary patterns in a sample of subjects with early psychosis. We studied 124 early psychotic disorder (PD) patients, 36 At‐Risk Mental States (ARMS) and 62 healthy subjects (HS).