Loading metrics Open Access Peer-reviewed Research Article James C. Vickers , Anna E. King, Graeme H. McCormack, Aidan D. Bindoff, Paul A. Adlard James C. Vickers, Anna E. King, Graeme H. McCormack, Aidan D. Bindoff, Paul A. Adlard Published: October 23, 2019 https://doi.org/10.1371/journal.pone.0224169 Figures Abstract There has been strong interest in the role of metals in neurodegeneration, and how ageing may predispose the brain to related diseases such as Alzheimer’s disease.