1 Introduction Periodontitis is the second most prevalent oral disease, affecting 19% of the global adult population and imparting a large socioeconomic burden. It is characterized by the progressive destruction of periodontal tissues, which leads to the loss of teeth and masticatory dysfunction.[1] Moreover, periodontitis is closely related to the progression of systemic diseases such as atherosclerotic disease,[2] thus, seriously affecting the overall health of patients.
