1 Introduction In recent decades, obesity (OB) has become a pandemic.[1] Particularly, over two-thirds of females at their reproductive age are either overweight or OB, and the number shows no signs of decline.[2] Beyond its impacts on metabolic health, female OB at reproductive age also reduces oocyte quality,[3] contributing to decreased fertility rates worldwide, even in conjunction with assisted reproductive techniques like in vitro fertilization.[4] Besides, the suboptimal oocyte...