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Articles by Guoping Wu
Comparative Comprehension on the Multioriginated Chinese Herb Murrayae Folium et Cacumen: From Chemical Compositions to Pharmacological Activities
Guanding Zhao, Guoping Wu, and Junming Chen contributed equally to this work. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References 1, , , et al., “Comprehensive Comparison on the Anti-Inflammatory Effects of Three Species of Sigesbeckia Plants Based on NF-κB and MAPKs Signal Pathways In Vitro,” Journal of Ethnopharmacology 250 (2020): 112530, https://doi.org/10.1016/j.jep.2019.112530.
Ameliorating Effects of Murraya paniculata (L.) Jack Extract on Arthritis via Suppressing Multi‐Target‐Mediated Synovial Hyperplasia, Inflammation, and Oxidative Stress
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References 1, , , et al., “Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II-Induced Arthritis Through Inhibiting Multi-Target-Mediated Synovial Hyperplasia and Inflammation,” Frontiers in Pharmacology 11 (2020): 547913, https://doi.org/10.3389/fphar.2020.547913.
Histone methyltransferase enzyme enhancer of zeste homolog 2 counteracts ischemic brain injury via H3K27me3‐mediated regulation of PI3K/AKT/mTOR signaling pathway
Background Epigenetic histone methylation plays a crucial role in cerebral ischemic injury, particularly in the context of ischemic stroke. However, the complete understanding of regulators involved in histone methylation, such as Enhancer of Zeste Homolog 2 (EZH2), along with their functional effects and underlying mechanisms, remains incomplete.
An aggregation-induced emission luminogen combined with a cyanoacrylate fuming method for latent fingerprint analysis
An aggregation-induced emission luminogen combined with a cyanoacrylate fuming method for latent fingerprint analysis Fingerprint remains topologically unchanged in one’s whole life, and therefore, has been used as a means to biometrically identify individuals in forensic investigations, law enforcement and access control. Appropriate methods are essential to obtain high-quality fingerprint images.
VSIG‐3 as a ligand of VISTA inhibits human T cell function
B7 family members and their receptors play a central role in the regulation of T cell responses through T cell costimulation and coinhibition pathways that constitute very attractive targets for the development of immunotherapeutic drugs. In this study, we report that VSIG‐3/IGSF11 is a ligand of B7 family member VISTA/PD‐1H and inhibits human T cell functions through a novel VSIG‐3/VISTA pathway.
Immune modulation by butyrophilin 1A1 (BTN1A1)
The butyrophilins are B7-like T cell co-regulatory molecules. These molecules are of increasing interest in cancer immunotherapy as they may represent a novel subset of immune check-point regulators. In this study, we expressed the recombinant human butyrophilin 1A1 extracellular domain with a C terminal 6-His tag (BTN1A1) in NSO mouse myeloma cell line, and investigated the biological functions of the purified recombinant BTN1A1 protein in vitro.
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