High levels of tumour infiltrating lymphocytes (TILs) at diagnosis were shown to be associated with decreased distant recurrence rates in triple negative breast cancer (BC) and increased trastuzumab (T) benefit in HER2+ disease.1 However, conflicting data showed that HER2+ cases with high TILs might not benefit from the addition of T to chemotherapy.2 Moreover, emerging literature suggests association between high tumour-associated macrophages (TAMs) and poor prognosis in patients with BC.3...
