AbstractBackground: Induced sputum is the best available noninvasive assessment of bronchial inflammation in asthma. However, reproducibility and validity in normal subjects have limited its use for proof of concept studies. Therefore we studied the characteristics of healthy volunteers (HV) and asthma patients (AP) in sputum induction (SI).Method: HV and AP recruited in a phase 1 unit for participating in respiratory early phase studies, with SI in the baseline screening were included.
