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Abstract Heart failure is often diagnosed only when symptoms become acute, but early detection could help prevent disease progression. As patient-reported quality of life is strongly associated with heart failure outcomes, it may also serve as an additional correlate with the disease before symptoms occur. This cross-sectional study investigates the associations of quality of life and asymptomatic heart failure and was conducted as an exploratory, hypothesis-generating analysis.
Précis: A GLS-based screening and prevention program for pre-HF in an at-risk population results in additional costs and benefits compared to standard of care. Authorship Confirmation: All authors certify that they meet the ICMJE criteria for authorship.
Results on guideline adherence The study results differ in the extent of guideline adherence, particularly between studies that did not examine the same treatment decisions.
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