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Hector M. Picon

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Articles by Hector M. Picon

Efficacy of Rac and Cdc42 inhibitor MBQ-167 in triple negative breast cancer

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By Hector M. Picon, Héctor Picón, Ailed Cruz-Collazo, Jean F Ruiz-Calderon, Luis D Borrero-Garcia
| mct.aacrjournals.org
Research Article Ailed Cruz-Collazo, Jean F Ruiz-Calderon, Hector Picon, Luis D Borrero-Garcia, Irmaris Lopez, Linette Castillo-Pichardo, Maria del Mar Maldonado, Jorge Duconge, Julia I Medina, Marvin J Bayro, Eliud Hernandez-O'Farrill, Cornelis P Vlaar and Suranganie Dharmawardhane DOI: 10.1158/1535-7163.MCT-21-0348 Abstract Triple Negative Breast Cancer (TNBC) is an aggressive form of breast cancer, with a high predisposition for locally invasive and metastatic cancer.
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A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis

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By Emily Powell, Jiansu Shao, Hector M. Picon, Christopher Bristow
| Nature Verified
Abstract Tumor cells disseminate early in tumor development making metastasis-prevention strategies difficult. Identifying proteins that promote the outgrowth of disseminated tumor cells may provide opportunities for novel therapeutic strategies. Despite multiple studies demonstrating that the mesenchymal-to-epithelial transition (MET) is critical for metastatic colonization, key regulators that initiate this transition remain unknown.
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