CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. REFERENCES , , , , , , , & (2021). Osteosarcoma in children: Not only chemotherapy. Pharmaceuticals, 14(9), 923. https://doi.org/10.3390/ph14090923 , , , & (2021). Hsa_circ_0004674 promotes osteosarcoma doxorubicin resistance by regulating the miR-342-3p/FBN1 axis. Journal of Orthopaedic Surgery and Research, 16(1), 510. https://doi.org/10.1186/s13018-021-02631-y , , , , , , , , , & (2020).