Get full text access Log in, subscribe or purchase for full access. References 1. Ito, T ∙ Ando, H ∙ Suzuki, T ∙ et al. Identification of a primary target of thalidomide teratogenicity Science. 2010; 327:1345-1350 2. Fischer, ES ∙ Böhm, K ∙ Lydeard, JR ∙ et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide Nature. 2014; 512:49-53 3. Matyskiela, ME ∙ Zhang, W ∙ Man, HW ∙ et al. A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos J Med Chem.