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To the Editor, Internal tandem duplications (ITD) of the FMS-like Tyrosinkinase 3 (FLT3) are detected in up to 30% of all newly diagnosed acute myeloid leukemia (AML) cases, with a decreasing prevalence in elderly patients [1]. FLT3-ITD positivity in AML patients predicts poor prognosis and shorter median overall survival (OS), corresponding to an intermediate genetic risk classification per the ELN 2024 less-intensive score [2].
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