Untargeted Urine Metabolite Profiling by Mass Spectrometry Aided by Multivariate Statistical Analysis to Predict Prostate Cancer Treatment Outcome Yiwei Ma, Zhaoyu Zheng, Sihang Xu, Athula Attygalle, Isaac Yi Kim and Henry Du Abstract Deciphering metabolomic networks has been demonstrated to provide valuable information for diagnosing and monitoring diseases. Herein, we report a technique to monitor untargeted urine metabolites to evaluate prostate cancer aggressiveness and treatment outcome.