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Articles by Heping Li
Multiomics profiling identifies molecular signatures of meat quality in sika deer cuts
Abstract Sika deer (Cervus nippon hortulorum) meat is increasingly recognized for its nutritional and culinary value, yet the molecular mechanisms underlying its quality traits remain poorly understood. In this study, we performed integrated transcriptomic, proteomic, and metabolomic profiling of six representative muscle cuts from farmed sika deer (n = 12). Intercostal and trapezius muscles exhibiting enriched features related to tenderness, marbling, and flavor.
Ferroptosis in autoimmune uveitis: potential links to blood–retinal barrier dysfunction and retinal inflammation
Abstract Autoimmune uveitis (AU) is a vision-threatening intraocular inflammatory disease characterized by disruption of ocular immune privilege, blood-retinal barrier (BRB) dysfunction, and progressive immune-mediated retinal injury. Although corticosteroids and conventional immunosuppressive therapies remain clinically effective, their long-term use is limited by adverse effects, relapse, and incomplete disease control.
Recent Advances in the Synthesis of 1,4-Enynes and Their Applications in Organic Synthesis
, , , , , , Recent Advances in the Synthesis of 1,4-Enynes and Their Applications in Organic Synthesis, The Chemical Record2026, 0, e70213. https://doi.org/10.1002/tcr.70213 Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Data sharing is not applicable to this article as no new data were created or analyzed in this study. References 1, , and , “Non-Metathesis Ruthenium-Catalyzed CC Bond Formation,” Chemical Reviews 101 (2001): 2067.
Annealing of skyrmion lattice in van der Waals magnet via field modulation
Abstract In atomic solids, annealing transforms disordered structures into ordered crystals through thermal activation, whereas realizing a comparable process in quasiparticle lattices is highly desirable. Magnetic skyrmions are topological spin textures that can form ordered lattice and undergo equilibrium phase transitions, yet thermal activation is insufficient to overcome their kinetic constraints or provide tunable control.
Grape seed proanthocyanidins supplementation attenuates diquat-induced intestinal barrier damage in weaned pigs
Abstract Objective: Grape seed proanthocyanidins (GSP) is a kind of plant polyphenols with a wide variety of biological activities. In the present study, we evaluated whether GSP can alleviate intestinal injury in weaned pigs injected with diquat. Methods: A total of 32 pigs were randomly assigned to four groups (n = 8): (1) nonchallenged control; (2) control + 50 mg/kg GSP; (3) diquat-treated control and (4) diquat + 50 mg/kg GSP.
Host selection in Megabruchidius dorsalis under storage conditions: investigating the role of visual, gustatory and olfactory cues in feeding and reproductive behaviors
CONFLICT OF INTEREST The authors declare that they have no known competing financial interests or personal relationships that could have influenced the work reported in this paper. DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description ps70875-sup-0001-Tables.docxWord 2007 document , 56.5 KB Table S1. Statistical parameters of Mixed-effects GLMs. Table S2.
Phenology-guided deep learning for automated rice mapping using SAR time-series imagery
?Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax in order to improve their display. Uncheck the box to turn MathJax off. This feature requires Javascript. Click on a formula to zoom. Abstract Accurate and timely rice mapping at regional scales is essential for global food security monitoring, agricultural policy development, and sustainable intensification efforts.
Health risk assessment of air pollution in Xinjiang, Northwest China - Scientific Reports
Abstract Air pollution disrupts ecological stability, threatens public health, and increases the risk of associated diseases. This study analyzed the spatiotemporal variations of six criteria pollutants from 2015 to 2024 in Xinjiang and their associated health risks using air quality index (AQI), aggregate air quality index (AAQI) and health risk indices (equivalent health risk–based index (EHAQI) and excess risk (ER)).
Single-cell transcriptome analysis reveals elongation and ossification characteristics of antlers
Introduction Only antlers have the unique capacity to grow rapidly and regenerate periodically every year. Previous studies have demonstrated that antlers are constantly undergoing growth and ossification through the coordinated activities of velvet, mesenchymal, cartilage, transition, and pre-cartilage cells (1). In addition, the skin, nerves, blood vessels, and fibrous tissue of the antler also undergo rapid growth.
Enantioselective Synthesis of Tetrahydroanthraquinones via Pd-Catalyzed Asymmetric [2 + 4] Annulation
Organic Letters Cite this: Org. Lett. 2025, XXXX, XXX Click to copy citationCitation copied! Learn about these metrics Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days. Citations are the number of other articles citing this article, calculated by Crossref and updated daily.
Molecular dynamics study on the effect of pressure on the combustion of NEPE propellant
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SAR Image Despeckling Based on Denoising Diffusion Probabilistic Model and Swin Transformer
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A synthesized sphalerite standard for in situ analysis of sulfur isotopes and trace elements by LA-MC-ICP‒MS and LA-ICP‒MS
A synthesized sphalerite standard for in situ analysis of sulfur isotopes and trace elements by LA-MC-ICP‒MS and LA-ICP‒MS In situ microanalysis of the sulfur (S) isotope composition and elemental distribution in sphalerite are important in geochemistry. Matrix-matched reference material is still deficient for in situ microanalysis. In this study, a hydrothermal synthesis method combined with hot-press sintering processes was used to synthesize a ZnS material Sph-LD.
A consensus genome of sika deer (Cervus nippon) and transcriptome analysis provided novel insights on the regulation mechanism of transcript factor in antler development | BMC Genomics | Full Text
We assembled a high-quality consensus genome of male sika deer using 143.03G (53–55 ×) Illumina short reads (from Han et al.2022), 96.39G (36–37 ×) PacBio hifi longs reads (from Han et al.2022), 161G (57–64 ×) Oxford Nanopore longs reads (from Qin et al.2023), and 263.03G (99–104 ×) Hi-C paired-end reads (from Han et al.2022) (Supplementary Table S1) [5, 9].
Assessing the Prognostic Value of Inflammation-Based Scores in Patient
Fang Wang,1,* Chang Jiang,2– 4,* Wenzhuo He,2– 4,* Heping Li,1 Gui-Fang Guo,2– 4 Lixia Xu1 1Department of Oncology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong Province, People’s Republic of China; 2State Key Laboratory of Oncology in South China, The Sun Yat-Sen University Cancer Center Guangzhou, Guangzhou, Guangdong Province, People’s Republic of China; 3Collaborative Innovation Center for Cancer Medicine, The Sun Yat-Sen University Cancer...
Synergistic modulation of oxygen vacancies and heterojunction structure in Pd@CN@TiO2 promotes efficient photocatalytic Suzuki-Miyaura CC coupling reactions - Sun - Applied Organometallic Chemistry - Wiley Online Library
Supporting Information Filename Description aoc7353-sup-0001-Supporting Information.docxWord 2007 document , 6.8 MB Table S1. Changes in the quality of the catalyst during preparation. Figure S1. HR-TEM image of the g-C3N4 material. Figure S2. HR-TEM image of the TCN-2 material. Figure S3. HR-TEM image of the TCN-4 material. Figure S4. HR-TEM image of the TCN-6 material. Figure S5. HR-TEM image of the TiO2 material. Figure S6. XPS spectra of the catalyst TCN-4. Figure S7.
Thermochemically synthesized α‐Al2O3 composite coating with high bonding strength and deuterium permeation resistance
Hydrogen isotope permeation in structural steels can cause severe issues including steel brittleness, fuel loss, and radioactive pollution in fusion reactors. To tackle this issue, we report a simple synthesis ofα-Al2O3/AlPO4 composite coating by the thermochemical reaction method to serve as a effective barrier hampering hydrogen isotope permeation. This coating was formed at 500°C and composed ofα-Al2O3 and AlPO4 phases.
Elevated FAM134B expression induces radiation-sensitive in hepatocellular carcinoma - BMC Cancer
Cell culture The HCC cell lines used in this study were purchased from the American Type Culture Collection (ATCC, Manassas, VA, USA) and were grown in Dulbecco’s modified Eagle’s medium (add with 10% fetal bovine serum) and cultured in a humidified incubator (37 °C, 5% CO2 atmosphere). Tissue specimens Our study included 132 patients diagnosed as HCC. The details of clinical tumor tissues are listed in the Tables 1 and 2.
An Automatic Method for Rice Mapping Based on Phenological Features with Sentinel-1 Time-Series Images
Abstract : Rice is one of the most important staple foods in the world, feeding more than 50% of the global population. However, rice is also a significant emitter of greenhouse gases and plays a role in global climate change. As a result, quickly and accurately obtaining the rice mapping is crucial for ensuring global food security and mitigating global warming.
Condensation and asymmetric amplification of chirality in achiral molecules adsorbed on an achiral surface - Nature Communications
Saturated adsorption of achiral CO molecules on various substrates have been observed to form stable phases consisting of clusters due to spontaneous condensation at low temperature. For examples, hexamer and heptamer structures have been suggested on the (111) plane of bulk α-CO33,34,35, as well as a CO adlayer on graphite36, Ag(111)37 and Cu(111)38.
Microwave pulse generation via employing an electric signal modulator to achieve time-domain mode locking in an optoelectronic oscillator
An actively mode-locked optoelectronic oscillator (OEO) is proposed and demonstrated to generate chirp-free microwave pulse trains with variable repetition rates. Time-domain mode locking is realized by using an electric signal modulator to achieve amplitude modulation of the generated microwave signal in the OEO cavity.
Molecules
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OSA | Broadband high-resolution microwave frequency measurement based on photonic undersampling via using three cavity-less optical pulse sources with coprime repetition rates
Abstract A photonic-assisted broadband and high-resolution microwave frequency measurement scheme is proposed and demonstrated based on undersampling via using three cavity-less optical pulse sources with coprime repetition rates. After undersampling by three ultrashort pulse trains with repetition rates in the order of gigahertz, input microwave signal is down-converted to three intermediate-frequency (IF) signals located in the first Nyquist frequency range.
Vector dynamics of pulsating solitons in an ultrafast fiber laser
Abstract We experimentally investigate the vector nature of various pulsating solitons in an ultrafast fiber laser with single-wall carbon nanotubes. By virtue of the dispersive Fourier transform technique, the polarization-resolved spectral evolution of pulsating vector solitons is measured in real time. In the case of single-periodic pulsation, pulsating behaviors of the two orthogonal polarization components can be either synchronous or asynchronous.
Recent Advances in Tin: From Two-Dimensional Quantum Spin Hall Insulator to Bulk Dirac Semimetal
An atomic layer of tin in a buckled honeycomb lattice, termed stanene, is a promising large-gap two-dimensional topological insulator for realizing room-temperature quantum-spin-Hall effect and therefore has drawn tremendous interest in recent years.
Study on biochemical mechanisms of micro-wave ablation on lung cancer by ex vivo confocal Raman microspectral imaging
Study on biochemical mechanisms of micro-wave ablation on lung cancer by ex vivo confocal Raman microspectral imaging As a highly invasive and the most prevalent malignancy, lung cancer remains the leading cause of cancer-associated mortality worldwide, especially in China. Microwave ablation (MWA) is a type of effective, safe, and least invasive ablative treatment modality, which has been increasingly used for management of unresectable lung tumors.
Deep learning control model for adaptive optics systems
Abstract To correct wavefront aberrations, commonly employing proportional-integral control in adaptive optics (AO) systems, the control process depends strictly on the response matrix of the deformable mirror. The alignment error between the Hartmann–Shack wavefront sensor and the deformable mirror is caused by various factors in AO systems. In the conventional control method, the response matrix can be recalibrated to reduce the impact of alignment error, but the impact cannot be eliminated.
Pressure-induced irreversible amorphization and metallization with a structural phase transition in arsenic telluride
The structural, vibrational and electronic properties of ?-As2Te3 under different pressure environments were investigated using a diamond-anvil cell (DAC) in conjunction with AC impedance spectroscopy, Raman spectroscopy, atomic force microscopy and high-resolution transmission electron microscopy up to ~25 GPa. Under non-hydrostatic conditions, ?-As2Te3 endured a structural phase transition at ~6 GPa, and a ~2 GPa delay in the transition point was observed under hydrostatic conditions.
Novel heterostructured InN/TiO2 submicron fibers designed for high performance visible-light-driven photocatalysis
As a typical photocatalyst, TiO2 can only absorb the UV light limited by its wide band gap, which severely limits its industry application. Seeking for effective strategies to enable its visible light absorption is on the spotlight. In this paper, InN with a band gap of 0.7 eV was incorporated into TiO2 nanofiber to obtain high-performance visible-light photocatalyst for the first time.
Abstract | Digital Library
We investigated the influence of dissolved calcium fluoride, CaF (aq), on the electrochemical dissolution of pyrite and the corresponding environmental effects on acid mine drainage (AMD). The experimental results showed that CaF (aq) promotes pyrite electrochemical dissolution. When the CaF (aq) concentration increased from 0 to 10 mg L–1 up to saturation, the promoting efficiency was 15.80 and 57.25%, respectively.
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