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1 Introduction Cue exposure reinforces alcohol misuse [1]. Through repeated pairing alcohol consumption with visual, social, environmental and other contextual stimuli, these cues acquire motivational salience and become associated with alcohol-related reward and reinforcement [1]. As a result, exposure to alcohol cues can elicit conditioned responses, including craving and approach behaviours, even in the absence of alcohol availability [2].
Abstract Despite evidence for sex differences in age-related changes in functional connectivity (FC), extant age-prediction studies have relied on mixed-sex samples. We applied connectome-based predictive modeling (CPM) on whole-brain resting-state FCs (parcellated into 100/16-cortical/subcortical regions) from the Human Connectome Project-Aging (age 36–100 years) dataset, separately for males (M; n = 263) and females (F; n = 339).
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