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1 INTRODUCTION Pancreatic islets are micro-organs dispersed throughout the pancreatic tissue, accounting for 1%–2% of wet weight mass in this organ.1, 2 Within islets, β cells are relatively more abundant than the other cell types (α, γ, δ and ɛ cells). The proportion and distribution of β cells relative to the other islet cell types are different in humans compared to rodents.
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