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Abstract This study investigated whether combined treatment with kaempferol and epigallocatechin-3-gallate (EGCG) offers superior protection during the in vitro maturation (IVM) and subsequent embryonic development of bovine oocytes compared to treatment with either agent alone. The underlying mechanisms were also examined. Preliminary dose–response assays revealed 0.1 µM kaempferol and 20 µM EGCG as the optimal concentrations when used individually.
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