Self-Assembled Nanoplatform with ZIF-8 as a Framework for FRET-Based Glutathione-Sensing in Biological Samples Yujie Ding, Hu Zhongfei, Yiming Zhao, Cai Shi, Shijie Zhang and Zongrui Zhang Abstract A glutathione (GSH) optical sensor with high sensitivity and exceptional selectivity was established for the first time. Zeolitic imidazolate framework-8 (ZIF-8) as a model was used for the first time to entrap Mn2+: ZnS quantum dots (QDs) and a Rhodamine B derivative (RBD) by self-assembly.