Skip To Main Content
Hui-chang Bi on Muck Rack

Hui-chang Bi

As seen in: Nature
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile
Back to Hui-chang Bi’s profile

Articles by Hui-chang Bi

Inhibition of histone deacetylase 3 alleviates lithocholic acid-induced intrahepatic cholestasis by enhancing expression of bile acid and lipid homeostasis-related genes

|
By Jing-Shu Li, Xiao-wen Jiang, Pei-Bin Chen, Xuan Li, Xiao Yang, Yue Gao, Jian-Hong Fang, Feng Qiu, Hui-chang Bi, Shi-cheng Fan
| Nature Verified
Abstract There is a lack of effective therapies for cholestatic liver injury. Recent studies have shown that pan-inhibitors of histone deacetylases (HDACs) play a protective role in cholestasis and fibrosis, but the dynamic changes and role of histone deacetylase 3 (HDAC3) under these conditions remain unclear.
Open in Who Shared Issue with article?

Xanthine oxidase activity in thiopurine curative Chinese inflammatory bowel disease patients

|
By Hui Liu, Xiang Gao, Fang-bin Zhang, Hui-chang Bi
| Wiley Online Library Verified
Abstract Xanthine oxidase (XO) competes with thiopurine S-methyltransferase (TPMT) and hypoxanthine guanine phosphoribosyltransferase (HPRT) to metabolize azathioprine (AZA)/6-mercaptopurine (6-MP) in vivo. A retrospective investigation was performed to detect the activity of XO in thiopurine curative Chinese inflammatory bowel disease (IBD) patients. We also evaluated whether a relationship between XO activity and incidence of thiopurine-induced adverse effects (AEs) existed.
Open in Who Shared Issue with article?
Show More