Introduction The coexistence of psoriasis and atopic dermatitis (AD) is rare due to the contrasting immune responses involved in their pathogenesis.1,2 Mechanistically, AD is characterized by an abnormal type 2 immune response, driven by Th2 cells producing interleukin (IL)-4 and IL-13, whereas psoriasis is primarily a Th1/Th17 inflammatory condition marked by elevated levels of IL-17A/F and IL-23.3–5 The divergent underlying mechanisms of these two skin disorders present significant...