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Ian Lock

As seen in: Color Research & Application, PLOS ONE
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Articles by Ian Lock

Mis-splicing drives loss of function of p53E224D point mutation

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By Ian Lock, Nathan H. Leisenring, Warren Floyd, Eric Xu
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Lock IC, Leisenring NH, Floyd W, Xu ES, Luo L, Ma Y, et al. (2025) Mis-splicing drives loss of function of p53E224D point mutation. PLoS ONE 20(3): e0318856. https://doi.org/10.1371/journal.pone.0318856 Editor: Swati Palit Deb, Virginia Commonwealth University, UNITED STATES OF AMERICA Received: September 3, 2024; Accepted: January 22, 2025; Published: March 5, 2025 Copyright: © 2025 Lock et al.
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Radiation-induced phosphorylation of a prion-like domain regulates transformation by FUS-CHOP

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By Mark Chen, Joseph P. Foster, Ian Lock, Nathan H. Leisenring
| cancerres.aacrjournals.org
Research Article Mark Chen, Joseph P. Foster, Ian C Lock, Nathan H Leisenring, Andrea R. Daniel, Warren Floyd, Eric Xu, Ian J. Davis and David G. Kirsch DOI: 10.1158/0008-5472.CAN-20-1497 Abstract Chromosomal translocations generate oncogenic fusion proteins in approximately one-third of sarcomas, but how these proteins promote tumorigenesis is not well understood.
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Genetic drivers and cells of origin in sarcomagenesis

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By Sarmishta Kannan, Ian Lock, Benjamin B. Ozenberger, Kevin Jones
| Wiley Online Library Verified
Invited Review Kevin B. Jones Corresponding Author kevin.jones@hci.utah.edu orcid.org/0000-0003-1531-2157 Departments of Orthopedics and Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, 84112 USA Correspondence to: Kevin B. Jones, 2000 Circle of Hope Drive, Room 3726, Salt Lake City, UT 84112, USA.
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