This 22th edition of the NAT (« Nantes Actualités Transplantation ») annual meeting was co-organized for the second time with the LabEx IGO network (« Immuno-Graft Oncology »). This international meeting was held on 1 and 2 June 2017 in Nantes (Western of France). The topic of this 2-days meeting was “Immunotherapies in transplantation and cancer”. This meeting brought together 17 international invited speakers, young researchers and 220 attendees mainly from Europe and North America.