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1 Introduction The canonical Wnt/β-catenin signaling pathway is a highly intricate and conserved process that plays a vital role in various developmental and physiological functions, such as embryonic development, stem cell maintenance, and tissue homeostasis (Clevers and Nusse, 2012). In embryonic development, Wnt/β-catenin pathway is crucial for tissue differentiation, cell fate determination, and organogenesis.
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