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1 Introduction Sjögren's disease (SD) is a chronic, systemic autoimmune disorder that principally targets the exocrine glands. Its hallmark clinical features—xerostomia and keratoconjunctivitis sicca—arise from progressive dysfunction of the salivary and lacrimal glands, respectively [1]. Beyond exocrine-gland involvement, SD can affect the lungs, kidneys, liver, and nervous system, underscoring its systemic nature.
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