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Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Mutations in MEFV, which encodes the cytosolic pattern recognition receptor pyrin, are linked to the autoinflammatory disorder familial Mediterranean fever (FMF), but mechanisms linked to mutations in the B30.2 domain of pyrin have been unresolved. A trio of studies by Aoki et al., Feng et al., and Iwata et al.
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