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1 WHAT IS KNOWN AND OBJECTIVE The legislature of the State of Hawaii of the United States touched off a firestorm of controversy with a decision to ban the two most commonly used sunscreen agents. The intent of the legislation is protection of coral reefs.1 The ban goes into effect in Hawaii on January 1, 2021, but proponents predict that similar bans will soon spread to other areas of the world that have coral reefs (Figure 1).
What is known and objective The double‐helical conformation of human DNA (hDNA) is so axiomatic that it is called the “canonical” form. Recently, though, intrastrand folds (“I‐motifs” and “G‐quadruplexes”) have been identified in hDNA. These could be targets for novel drug discovery. Any interruption of the canonical form of hDNA fundamentally impacts the normal progression of transduction and translation.
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