1. Introduction Infective endocarditis (IE) is defined as a microbial infection of the endocardial surface. It represents “infection of the endocardium with the presence of microorganisms at the level of the lesion”, specifying that it may be in the valvular endocardium, parietal or septal defects, or a persistent arterial channel. This descriptive formulation emphasizes the initial endocardial changes, which are more common in approaches to the condition from a cardiological perspective [1,2].