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What Is New? The experience of a negative emotion including anger, anxiety, and sadness is common and associated with an increased risk of cardiovascular disease events. There are scarce data on the effects of provoked anger, anxiety, and sadness on vascular endothelial health. In the current study, the provocation of anger adversely affected endothelial health by impairing endothelium‐dependent vasodilation.
Association of day-level pain with exercise Tables 3 and 4 display results of the GLMMs estimating day-level total pain score and difference. Coefficients for the model interaction terms indicated a small but statistically significant moderation of previous-day exercise by habitual exercise frequency (rate ratio=0.96 for total pain score and −0.14 for pain score difference, p<0.05; see figure 3).
Worsening depressive symptoms and walking impairment are significant burdens in multiple sclerosis. We explored the reciprocal relationship between depressive symptoms and walking impairment in a cohort of 269 people with relapsing-remitting multiple sclerosis over 2?years. The data were examined using longitudinal panel analysis in Mplus.
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